App1: An Antiphagocytic Protein That Binds to Complement Receptors 3 and 2
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چکیده
منابع مشابه
Role of glucose in the expression of Cryptococcus neoformans antiphagocytic protein 1, App1.
The cryptococcus-specific protein antiphagocytic protein 1 (App1) regulates Cryptococcus neoformans virulence by controlling macrophage-driven fungal phagocytosis. This is accomplished through complement receptors (CR), specifically CR3. When inhaled, C. neoformans can cause a life-threatening meningoencephalitis in immunocompromised patients. Because glucose starvation can significantly change...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2008
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.182.1.84